University of Pennsylvania DIRECTOR, THERAPEUTIC DEVELPMENT,NEURODEGENERATIVE in Philadelphia, Pennsylvania

DIRECTOR, THERAPEUTIC DEVELPMENT,NEURODEGENERATIVE Below you will find the details for the position including any supplementary documentation and questions you should review before applying for the opening. To apply for the position, please click the Apply for this Job link/button.

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Posting Details

Posting Details

Reference Number 40-28430


School Name Perelman School of Medicine

Org OD-Center for Orphan Disease Research and Therapy

Posted to the Web 10/02/2018

Posted Job/Salary Grade 030

Employment Type Exempt

Hours N/A

Position Type Full Time

Position Schedule 8am - 5pm

Months 12

Position Length Contingent Upon Funding

Position End Date

University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

School/Center Overview

The Perelman School of Medicine at the University of Pennsylvania is the oldest and one of the finest medical schools in the United States. Penn is rich in tradition and heritage and at the same time consistently at the forefront of new developments and innovations in medical education and research. Since its founding in 1765 the School has been a strong presence in the community and prides itself on educating the leaders of tomorrow in patient care, biomedical research, and medical education.


Orphan diseases represent a collection of disorders that afflict fewer than 200,000 individuals for any single disease type, yet there are more than 7,000 distinct orphan diseases. The Orphan Disease Center (ODC) in the Perelman School of Medicine was founded in 2011 to promote and fund research in rare diseases globally, beyond Penn, making a difference for these under-served patient populations. A unique aspect of ODC is that it is a ‘Center without walls’ which sources and contributes to developing transformative therapies through the use of platform technologies and of research strategies that can be deployed across multiple rare disease programs. The main feature is a pilot grant program which provides $8M annually to over 35 global institutions. We are currently seeking a new Director of Therapeutic Development to over see the Program of Excellence focused on Neurodegenerative Diseases.Reporting to the Executive Director of the Orphan Disease Center (ODC) and supporting a Program of Excellence, your goal will be to provide international leadership in establishing research agenda in rare disease that are a high priority of the ODC. You will be developing strong partnerships with key stakeholders, including patient advocacy groups, partnering academic institutions and key opinion leaders in relevant diseases by organizing international scientific symposiums related to diseases of interest to the program of excellence, partnering with ODC staff to organize these events. You will have the primary responsibility for creating and executing a strategic plan, to establish clinical development for novel therapeutics. You will seek advisement from all relevant stakeholders, including patient advocacy groups, ODC leadership, and external advisors in initial development of this plan. In executing this plan, you will undoubtedly be required to have extensive interactions with biopharmaceutical industry partners, knowledgeable on the development of novel therapeutics and will require you to travel to biomedical conferences. You will establish working groups within each disease to address research and clinical practice gaps, and focus on filling those gaps to further the development of effective treatments. You will be critical in the success of the program of excellence, providing careful oversight of the research conducted by grant recipients, assuring progress and progression of science towards a biopharmaceutical partnership. It will be essential that you have experience in biopharm to assure these critical links occur between the grant recipients and corporate partners. Joining the ODC offers you with unique opportunity to contribute to revolutionizing the practice of medicine for these under-served patient groups.


  • PhD with a background in Neurodegerative Diseases and 1 to 5 years of drug development experience required; MD preferred* Experience writing clinical development plans and clinical trials required* Experience with patient registries/natural history studies preferred* Preferred experience in rare diseases* Self starter but also a strong desire to contribute and work collaboratively to achieve goals* Success in roles requiring execution of multiple tasks while responding to multiple priorities* Highly functioning, detail-oriented, and analytical candidate who can think strategically* Excellent oral/written communication skills required

Affirmative Action Statement

Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

Special Requirements Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.

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Posting Supplemental Questions

Required fields are indicated with an asterisk (*).

  • How did you hear about this employment opportunity?

  • Jobs@Penn

  • Contacted by a Penn Recruiter

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  • What is your highest level of education completed?

  • Less than high school education

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  • Bachelor's Degree

  • Master's Degree

  • PHD/MD/JD or equivalent doctoral degree

  • How many years of experience do you have related to this position?

  • 0 to 1 Year

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  • 2 to 3 Years

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  • 5 to 7 Years

  • 7 to 10 Years

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Applicant Documents

Required Documents

  • Resume

Optional Documents

  • Cover Letter