University of Virginia Research Associate in Charlottesville, Virginia

Posting Summary:

The lab of Dr. Heather Ferris in the Division of Endocrinology and Metabolism at the University of Virginia is seeking applicants for a Post-doctoral Research Associate position focused on studying the impact of diabetes on cognitive function using animal and cell models of disease. The incumbent will be responsible for developing and implementing experiments in specified areas of research and will write grant proposals, manuscripts for publication, and abstracts for presentation at national and international meetings. Supervision and instruction of graduate and undergraduate students is also required.

Previous work in our lab has demonstrated that diabetes results in an impairment of brain cholesterol synthesis. We went on to show that genetic lowering of brain cholesterol levels leads to metabolic and cognitive disorders in mice independent of diabetes (Suzuki, PLoS Biology: PMC3621654, Ferris, PNAS: PMC28096339). Potential projects include: 1) determining the role of the insulin receptor in the development of Alzheimer's pathology, 2) further defining the impact of disrupted cholesterol metabolism on various cell populations in the brain in the presence and absence of Alzheimer's disease, 3) investigate changes in brain energetics in knock out and disease models, and 4) mechanistic studies of oxidized cholesterol species in the brain which may be an intermediary between diabetes and Alzheimer's disease.

Candidates must have a PhD and/or an MD in Neurosciences, Physiology or a related field in hand by start date, with a background in Neurosciences, as well as have extensive experience in conducting independent research, preparing manuscripts and supervising research trainees. The successful applicant should also be highly motivated, independent, and creative, and possess a strong work ethic and critical thinking abilities.

This position is restricted and is contingent upon funding.

To apply, visit https://jobs.virginia.edu and search on Posting Number 0621459. Complete a Candidate Profile online, attach a cover letter, curriculum vitae, contact information for 3 references and a statement of research interest.

For further information about the position, please contact Dr. Heather Ferris via e-mail at HF4F@hscmail.mcc.virginia.edu.

For further information about the application process, please contact Nicole Trice via e-mail at TNT6F@hscmail.mcc.virginia.edu.

Positions will remain open to applications until filled.

The University of Virginia is an equal opportunity and affirmative action employer. Women, minorities, veterans, and persons with disabilities are encouraged to apply

Required Applicant Documents:

CV / Resume Cover Letter Contact information for 3 References - name, email, phone Statement of Research Interest

EO/AA Statement:

The University of Virginia is an equal opportunity and affirmative action employer. Women, minorities, veterans and persons with disabilities are encouraged to apply.

If any experience is required, please specify kind of experience:

Primary cell culture, qPCR, Western blotting, histology.

Applicant should have hands on experience performing qPCR, western blotting and histology. Should have experience culturing primary cell lines.

If any experience is preferred, please specify kind of experience:

Experience with rodent models. Expertise in brain histology and culture of cells of the central nervous system.

1.Use of rodent genetic or induced models for in vivo modeling of disease. 2. Sectioning and staining of rodent brain for morphology and alterations in protein expression. 3. Culturing of neurons, astrocytes, oligodendrocytes, and/or microglia in primary cultures.

Rank: Research Associate

Department: Department of Medicine, Endocrinology and Metabolism

Academic Year for Position? (e.g. 2015): 2018

Closing Date: Open Until Filled

FLSA Exemption Status: Exempt

Is this position funded in whole or in part by the American Recovery & Reinvestment Act (Stimulus Package)?: No

Posting Date: 08-08-2017

Location: Charlottesville

Is this position eligible for an Alternate Work Schedule?: Yes

Employment Posting Category: Professional Research Staff

E-mail a Friend: jobs.virginia.edu/applicants/Central?quickFind=82485

Appointment Type: Professional Research Staff

Posting Number: 0621459

If degree or equivalent experience required, please specify:(Entries to the right will appear in the posting for this position.)Degree Requirements Analysis: PhD and/or an MD in Neurosciences, Physiology or a related field.

Number of Months/Year: 12

Drug Testing Required?(Typically positions involved in patient contact, mass transportation or law enforcement are included): No

Position Type: Professional Research Staff

Posting for UVA Employees Only: No

Employment Conditions: Criminal HistorySexual Offender RegistryInternational SearchDegree Validation

Shift: Day

Type of Application:(required to apply for this posting): Candidate Profile

Required ExperienceWhat is the minimum level of relevant experience required to successfully perform the duties and responsibilities of the position? Choose one.: Some - up to 4 years

Preferred EducationWhat level of education is preferred to successfully perform the duties and responsibilities of the position? Choose one.: No Response

Organization (Position Organization): 40745 MD-INMD Endocrinology

Preferred ExperienceWhat is the minimum level of relevant experience preferred to successfully perform the duties and responsibilities of the position? Choose one.: No Response

Number of Work Hours Per Week:(format: xx.xxxx): 40

Working Title: Research Associate

Is this position eligible for Telecommuting?: No

Required EducationWhat is the minimum level of formal education required to successfully perform the duties and responsibilities of the position? Choose one.: *Degree Required